Genomic testing can validate CIRS diagnosis and treatment success

The area of genomics is an emerging area that represents the ultimate in diagnosing CIRS and validating the success of the treatment. Genomic testing allows us to look at gene expression, which is the most reliable and promising way to look at DNA as it shows us patterns of gene expression and changes in gene regulation that can create illness. CIRS and other Illnesses are caused by the “lack of regulation” of regulation. By “lack of regulation”, we mean the body’s mechanisms that are designed to regulate and balance all of the inflammatory and regulatory processes fail and we get the cytokine storm and other effets of dysregulation that is charateristic of CIRS and other auto-immune diseases.

Assessing DNA transcriptomics give us a phenomenal amount of information about the state of the disease, risk factors for acquiring CIRS as well as other illnesses and can illustrate treatment success. The genomics testing is relatively expensive and totally out of pocket so it will not be a fit for all patients, but when economically feasible, the genomics testing is invaluable. The below images illustrate the power of genomic testing by showing gene expression and mitochondrial proteins before and after treatment for CIRS. Note that these are actual images from a real patient’s genomics test that had a confirmed case of CIRS before and after treatment for CIRS.



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The first set of images shows the gene expression present in the CIRS patient prior to treatment. Note the dysregulation that is illustrated in the picture mostly by the “up regulation” of inflammatory cells as denoted in red.

The second set of images shows the gene expression in the same CIRS patient AFTER treatment. Note the correction of the dysregulation that is illustrated in the picture by the absence of red (up regulation).

These images illustrate the power of genomics testing. For patients who can afford the additional cost, it provides a very personalized view of what is happening with gene expression allowing us to specifically target the dysregulation and validaing that treatment has restored the body to normal functioning.