Bioidentical Pellet Implant Therapy

Bioidentical Pellet Implant Therapy is a form of Bioidentical Hormone Replacement Therapy that involves placing small hormone pellets under the skin that are programmed for a slow release over a 3-5 month period of time. The pellets are molecularly identical to our endogenous human hormone, and are synthesized from an oil derived from yams. Pellets have been used with great success in the United States, Europe and Australia since 1938 and found to be superior to other methods of hormone delivery, so it is not either experimental or new. Pellets have been proven to deliver consistent, physiologic levels of hormones and avoid the fluctuations of hormone levels seen with other methods of delivery, including oral (tablets and capsules), transdermal (creams) and injection (testosterone for Men).

Unlike creams and oral methods that have to be taken or applied daily, or testosterone injections for men that have to be done weekly, pellets are inserted just under the skin and last for 3-5 months, slowly releasing the bioidentical hormone to the body through this entire period without any re-application or other maintenance.

Like the transdermal, oral and injection methods, pellets address many of the symptoms of hormone loss and aging including decreased bone density, increased fat, decreased muscle mass, increased fasting blood sugars, increased cholesterol, hot flashes, decreased libido, decreased energy, anxiety and depressive symptoms, sleep disturbances, poor erectile function, etc. For a broader description of BHRT in general, men may click here and women should click here.

As with other forms of BHRT, there have never been any findings of health risks when using relatively physiologic doses, nor logically should there be any since the bioidentical hormones have the same chemical structure as your natural hormones. In fact, over one hundred recent scientific studies show a lack of side effects and the measurable benefits of BHRT in symptomatic individuals. The Women’s Health Initiative Study points to the obvious: that pregnant mare urine derived hormones which are not molecularly nor physiologically identical to human hormones cause severe health issues attributable to differences in their mechanism of action. Most all of the dangerous “side effects” of non-bio-identical hormone treatment are absent when treating with bio-identical hormones. By now, I have shared the literature that supports these points, but if I haven’t and you are interesting in seeing it, just ask.

Please read our FAQ section below for the answers to many of your questions.

Frequently asked questions?

How are pellets inserted?

Using a local anesthetic, they are painlessly inserted under the skin of the hip, through a tiny incision, using a small insertion device. After the pellets are inserted, a small piece of tape is placed to close the incision. The entire process takes only a few minutes, and the amount of discomfort one feels is actually less than getting a blood test.

How many pellets are inserted?

For women, pellet implant therapy generally includes two pellets, one pellet each for testosterone and estradiol. For men, the number of testosterone pellets generally ranges between 6 and 8 pellets depending on size, untreated testosterone level and metabolism.

Which hormones are available in pellets?

Estradiol and testosterone are available for women and testosterone is available for men in pellet form. Other hormones will continue to be prescribed in an oral or transdermal form.

How long after the pellet insertion before patients feel the benefits of the therapy?

Some patients begin to ‘feel better’ within 24-48 hours while others may take a week or as long as 3-4 weeks to notice a significant difference. If you are transitioning from other forms of hormone therapy, we will work with you to avoid a gap in your therapy.

What are the advantages of Bioidentical Pellet Implant Therapy?

Bioidentical hormone pellet therapy is the only method of administering bioidentical hormones that gives sustained and consistent levels throughout the day, for 3 to 6 months, without any patient compliance issues.

What are pellets made from?

Pellets are synthesized from yams. They are either pure estradiol or pure testosterone. Other than a small amount of stearic acid as is common in pharmaceuticals, there are no other ingredients in them. They dissolve completely with no residual under the skin over a 3-6 month period.

The pellets are manufactured by specialized compounding pharmacies using ingredients (estradiol or testosterone) that are U.S.P. pharmaceutical grade. They are produced in a “clean room” to avoid contamination and other impurities.

Is everyone a candidate for Bioidentical Pellet Implant Therapy?

Most everyone is a candidate, but there are a few exceptions as follows:

  • Patients taking blood thinners may not be a candidate for the pellet insertion procedure itself due to the blood thinners adverse impact on clotting.  Depending on the particular medication, dosage and other factors, we may be able to overcome this issue.  If the prescribing physician would agree, the optimal situation is for the patient to avoid taking the blood thinners for one week before the procedure.
  • Men with extremely low body fat may not be a candidate for pellet insertion due to the possibility of pellet extrusion if there is not sufficient fat tissue at the pellet insertion point.  This is very rare but can happen in some slim, very athletic men that have body fat percentage of 10% or lower.
  • Patients with active breast or prostate cancer are not candidates for BHRT of any kind including BHRT Pellet Therapy.

What is the pricing for Bioidntical Pellet Implant Therapy?

The pricing for Bioidentical Pellet Implant Therapy is $875 per insertion for Men and $575 per insertion for women. It is expected that Men will require 3 insertions per year and women will require 4. The prices are higher for men because men receive 6 – 8 pellets whereas women receive 1 – 2 pellets. The pellet pricing include all of the program services that are included in our current Health Assurance I and II programs. This means that normal followup visits, monitoring, retesting and physician consults are included in the pellet insertion fee as long as the patient is only being prescribed any combination of Testosterone, Estradiol, Progesterone, Pregnenolone, and DHEA. Patients that using other medications like hCG, Sermorelin or HGH will still require separate program fees but the program fees.


“So far I have lost 30#’s in 6 weeks and have the energy of a 40 year old. Am so thankful to be able to handle unpacking and shelving 6000 books. I am up and down stepladders and extension ladders with books in tow. The awful arthritis pain is there but the energy isn’t depleted from the pain like before and I keep going like this for hours.”

LL - Winchester, VA

June4, 2009. “Good morning! I have to tell you that I weigh 157… down from 191!!! OMG…thank you so much! I feel incredible!”

KB – Reston, VA

Hi Lynese – In an old file I found a print out from an online longevity calculator I had used in 2007 ( I thought I was doing well because it said I would likely live to 86! But I just re-took the survey. Basically by cutting out the coffee, carbs and sugar, increasing my exercise and losing weight, I’ve apparently added 13 years to my life!! The calculator now says I could live to be 99!! With a little more exercise and a little less work, I could live to 106!! Thanks for all the added years Lynese!!!

All the best.

P.S. – I saw Diane over the weekend – she’s looking great, and is so happy with her weight loss.

AP - Falls Church, VA

You are so great! I truly appreciate all you are doing for me. Phyllis and I are so fortunate to have found you.

TB - Pottstown, PA

Dear Lynese,

Words cannot describe how happy I am with your anti-aging program. I have not felt this good in YEARS. Since getting pregnant in 1995 I have been overweight. Between 1992-1995 I was being treated for infertility and had to take all sorts of hormones that made me bloated and tired.

Now, at the age of 46 I have more energy and I look better than I have in YEARS. I actually THRIVE on exercise and do it religiously because I know it is the key to keeping the weight off and enjoying the foods that I love.

As a successful businesswoman, you often feel that you can’t have everything and I put my weight and health on hold to grow my business. You have given me the gift of being able to run a business AND look good. I am getting so much attention for my weight loss and it has helped my confidence and self esteem greatly.Since I do a lot of speaking engagements, I know that image is more important than what you say or how you say it. By looking better and appearing fit and healthy, I am a more powerful public speaker!

I can’t say enough about this gift you have given me and I hope you know how much I appreciate you.

On top of all of this, you are truly a beautiful person inside and out who provides a level of caring I have never seen from a doctor, weight loss clinic or other health professional.

HAVE A GREAT DAY!!!!!!!!!!!!!!

KB - Reston VA

Dare I say it out loud? It sure is looking as though Semorelin has given me my life back. I was so worried about skiing – afraid I’d ski one day and be in bed the rest of the week. But I was just fine. This past Saturday I prepared, served, and cleaned up (with help) dinner for 14. Sunday I was just fine.

SJ - McLean, Virginia

My update. I feel pretty good!!! My bleeding is under control and I am now regular for the most part. Sometimes I will have a strange menstral bleed (long and slow), but I will take it compared to my old “normal”. I still love the progesterone and testosterone I am on. They leave me with no side effects.

I was very happy at my recent (Feb 6th) annual doc appt (physical). After the standard blood draw work up, my numbers were:
Vitamin D= 66.9 (down a bit from your work up which was 77, but still good)
Cholesterol=123 (down from 150 in Sept 2011)
Triglycerides=91 (down from 129 in Sept 2011)

So… I am the new spokesperson for HCG! I love that stuff!! smile The second round for me was amazing. I was very disciplined and determined and after about the 3rd day, it become very easy for me. I was able to drop 14lbs in an 18 day cycle!!!! AND….I am keeping that off with very little effort! OMG I couldn’t be happier! I am in the body that I am comfortable in once again! That feels so good. I am continuing to eat clean and exercise, it is a great life change!

JG—Vienna, VA

Hi Lynese – Just had to share this with you. I have appeared in an online newsletter (Legal Bisnow) twice – the first time a year ago and the second time today. Look at the difference in my photos!

It’s an absolute miracle! In the older photo even my eyelids look fat! I can’t get over how much I now look like my old self – of 20 years ago! I certainly don’t look like I’m closing in on 59, do I??

The best thing anyone has said to me so far was a comment made by a neighbor who saw me today for the first time in over a year. At first he didn’t recognize me. Then he just stared intently into my face for a few minutes and said “How is your mother?” (I was confused because he doesn’t know my mother). Then he said “I had to ask that because you look like your own daughter!” Wow!

Thank you, thank you, thank you!!!

AP - Falls Church, VA

“With that said, I have been getting incredible compliments:
“You look like a movie star”
“What have you been doing”
“You look amazing”
“You look ten years younger”
I feel incredible”

KB - Reston, VA

Hi – hope you are doing well. Are you ready for Thanksgiving? I’m getting there. I wanted to let you know I hit the 30 lb loss today!!! Yeah! So excited! Clothes that didn’t fit are fitting. Clothes I used to wear are too big. Feeling great! A little nervous about tomorrow’s feeding frenzy- but hoping to not overindulge too bad.

LJ - Arlington, VA

Anyway – just had to tell you that my size 12 pants have been falling off of me! I went to Target this weekend to get some cheap crop pants and shorts for the summer – still not wanting to invest much in clothes that are not my “target” size. (I’ve blown past the size 14 shorts I couldn’t fit into for years). And wouldn’t you know – the 12s were too big – I fit best in the size 10!!

I’M A 10!!! I’m amazed!!

I broke the 170 barrier too – I’m now 168. Just 13 pounds to go to my goal weight. I can’t believe it. The meds have been working like a charm. I think the extra thyroid has really boosted me past a plateau. I’m cleaning out my closet like a madwoman; I can’t believe how much clothing I have for donations.

I’m still getting double takes and amazed looks from people who haven’t seen me for awhile. And after remarking how great I look, a girlfriend recently peered suspiciously at me and said – “And have you had something done to your face too? You look younger!” And I do!

AP - Falls Church, VA 6/2010

Hi Lynese — Great news – seems a fibroid has disappeared! The ultrasound revealed only one fibroid this time, and it is just a little teensy bit smaller than before. So it hasn’t gotten any bigger at all. And the other fibroid didn’t show up on the ultrasound. smile

Thank goodness I did not get that hysterectomy, huh? and thank goodness I came to you to start the bio-identical hormone therapy. I believe that the progesterone is working. And I’m so glad I’m not on the birth control pills anymore. BTW, haven’t had a period since September, and haven’t had any hot flashes either! Life is good.

AK - Germantown, MD

Social Media

Ready to get started? Click here to begin the online enrollment or click here to contact us on our quick contact form and someone will get back with you within 24 hours.